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. 2019 Sep 19;12:2961–2969. doi: 10.2147/IDR.S221788

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© 2019 Chi et al.

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The genetic environment of the bla_KPC-2 gene in K. pneumoniae was isolated from clinical sources. The arrows represent the direction of transcription. The red open reading frame (ORF) indicates the bla_KPC-2 gene, the pink ORF indicates the mobile element, the yellow ORF indicates other resistance genes or enzymes and the gray ORF indicates other genes or genes of unknown function. (A) The genetic environment of bla_KPC-2 is similar in isolates 2C1, 3C1, 3C2, 3C9, 3C17, 3C18, 3C29 and 4C5. (B) The isolates 3C3, 3C23 and 3C25 all carry bla_KPC-2 and share the identical genetic environment surrounding the same gene. (C) The isolate 3C21 and the isolate 4C2 have the same genetic environment. (D) The genetic environment of the isolate 3C11 carrying the bla_KPC-2 gene.