Figure 1. Expression of VEGFR2 and associated VEGFs are detected in pediatric cancer cell lines.
(A) Eleven pediatric cancer cell lines were evaluated for endogenous VEGFR2 protein expression. (B) Endogenous levels of VEGF-A (left), -C (middle), and -D (right) protein produced by 9 pediatric cancer cell lines in co-culture conditions were assayed by ELISA. Error bars represent SEM. Note the bro ken y-axis for VEGF-A. Abbreviations: ECFC, endothelial colony forming cell; NB, neuroblastoma; RB, retinoblastoma; OS, osteosarcoma; RMS, rhabdomyosarcoma; MRT, malignant rhabdoid tumor; ES, Ewing’s sarcoma.