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editorial
. 2019 Sep 17;10(53):5495–5496. doi: 10.18632/oncotarget.27173

Figure 1. Nicotinamide and NSAIDs are binding and inhibiting SIRT1 deacetylase.

Figure 1

The enzymatic inhibition by these molecules stimulates the anti-proliferative p53/P21 pathway reducing the risk of invasive breast cancer insurgence.