Table 4. Median (10th - 90th percentiles) values for HCY, vitamin B6, folate, hsCRP and IL-6 according to quartiles of age-corrected RTL in 1st (A), mid-range (2nd-3rd) and 4th (C) quartiles of B12 (n=2970, only subjects in whom the measurements of B12 and RTL were complete).
| (A) 1st quartile of B12 | |||
| Age-corrected RTL quartiles | |||
| 1, 2, 3 (n=582) | 4th (n=174) (LB12LT) | p-Value | |
| HCY (μmol/L) | 14.2 (9.1-23.8) | 12.8 (8.3-22.4) | <0.001 |
| Vitamin B6 (μg/L) | 7.3 (3.2-16.6) | 8.1 (3.2-17.5) | 0.237 |
| Folate (μg/L) | 6.7 (4.2-11.1) | 7.1 (4.7-11.3) | 0.152 |
| hsCRP (mg/L) | 3.40 (0.62-23.80) | 4.01 (0.52-26.25) | 0.458 |
| IL-6 (pg/mL) | 3.34 (1.21-11.51) | 3.39 (1.29-10.73) | 0.927 |
| (B) Mid-range (2nd -3rd quartiles) of B12 | |||
| Age-corrected RTL quartiles | |||
| 1, 2, 3 (n=1099) | 4th (n=366) | p-Value | |
| HCY (μmol/L) | 12.2 (8.4-18.8) | 11.8 (7.9-18.6) | 0.071 |
| Vitamin B6 (μg/L) | 8.9 (3.5-20.4) | 10.2 (3.7-22.4) | 0.006 |
| Folate (μg/L) | 7.6 (4.7-11.9) | 8.1 (4.9-11.6) | 0.382 |
| hsCRP (mg/L) | 3.16 (0.68-20.26) | 2.62 (0.62-17.55) | 0.055 |
| IL-6 (pg/mL) | 3.20 (1.21-11.18) | 2.73 (1.14-9.14) | 0.015 |
| (C) 4th quartile of B12 | |||
| Age-corrected RTL quartiles | |||
| 1, 2, 3 (n=546) | 4th (n=203) (HB12LT) | p-Value | |
| HCY (μmol/L) | 11.3 (7.2-20.1) | 10.7 (7.5-17.4) | 0.125 |
| Vitamin B6 (μg/L) | 9.8 (3.7-30.6) | 11.1 (3.9-29.7) | 0.274 |
| Folate (μg/L) | 8.8 (5.1-12.8) | 9.1 (5.0-12.9) | 0.555 |
| hsCRP (mg/L) | 3.91 (0.88-26.15) | 3.67 (0.43-21.64) | 0.006 |
| IL-6 (pg/mL) | 3.78 (1.28-13.1) | 2.62 (0.88-9.56) | <0.001 |
Statistically significant differences are reported in bold.