Table 5. Subgroup analysis according to the IVT patients with and without endovascular therapy.
Clinical outcomes | Patients with endovascular therapy (n = 85) | Patients without endovascular therapy (n = 478) | |||||
Euthyroidism (n = 60) | SHyper (n = 12) | SHypo (n = 13) | Euthyroidism (n = 351) | SHyper (n = 44) | SHypo (n = 83) | ||
Early neurological deterioration | |||||||
Unadjusted OR (95%CI) | Reference | 1.34 (0.36–5.20) | 0.23 (0.03–1.91) | Reference | 4.02 (1.99–8.14)* | 0.72 (0.31–1.66) | |
Adjusted OR (95%CI) | Reference | 1.17 (0.28–4.95) | 0.22 (0.03–1.96) | Reference | 4.72 (2.08–9.69)* | 1.08 (0.44–2.65) | |
Poor outcome at 3 months | |||||||
Unadjusted OR (95%CI) | Reference | 1.69 (0.19–9.94) | 0.25 (0.06–1.04) | Reference | 2.50 (1.30–4.83)* | 0.85 (0.30–4.83) | |
Adjusted OR (95%CI) | Reference | 1.40 (0.15–9.33) | 0.27 (0.08–1.06) | Reference | 2.54 (1.21–5.33)* | 0.84 (0.49–1.45) | |
Mortality at 3 months | |||||||
Unadjusted HR (95%CI) | Reference | 2.75 (0.85–6.54) | 0.39 (0.04–2.27) | Reference | 4.29 (2.63–9.03)* | 0.83 (0.29–2.44) | |
Adjusted HR (95%CI) | Reference | 1.77 (0.58–5.44) | 0.37 (0.06–2.31) | Reference | 3.99 (1.81–9.30)* | 0.89 (0.26–3.12) |
Abbreviations: CI: confidence interval; OR: odd ratio; HR: hazard ratio; SHyper: subclinical hyperthyroidism; SHypo, subclinical hypothyroidism.
*P < 0.05
Adjusted model was controlled for age, sICH, ASPECTS score at 24 h and vascular occlusion.