Table 1. Functional enrichment analysis of DEGs in atherosclerosis using GSEA.
| Gene set name | SIZE | ES | NES | Rank at max |
| Upregulated | ||||
| GO_SKELETAL_MUSCLE_CONTRACTION | 29 | 0.316 | 0.939 | 2942 |
| GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | 15 | 0.360 | 0.902 | 3373 |
| GO_ACTIN_FILAMENT_POLYMERIZATION | 20 | 0.393 | 1.205 | 2007 |
| GO_ACTIN_FILAMENT_BUNDLE_ORGANIZATION | 47 | 0.302 | 1.064 | 1726 |
| GO_CYTOSOLIC_CALCIUM_ION_TRANSPORT | 48 | 0.435 | 1.218 | 1988 |
| GO_CYTOSOLIC_PART | 192 | 0.256 | 1.011 | 3378 |
| Downregulated | ||||
| GO_SMOOTH_MUSCLE_CONTRACTION | 44 | −0.580 | −1.577 | 2784 |
| GO_MUSCLE_CONTRACTION | 220 | −0.514 | −1.573 | 2897 |
| GO_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | 60 | −0.505 | −1.422 | 2121 |
| GO_ACTIN_FILAMENT_ORGANIZATION | 158 | −0.308 | −1.195 | 2174 |
| GO_CYTOSOLIC_TRANSPORT | 188 | −0.237 | −1.144 | 2287 |
| GO_ENDOPLASMIC_RETICULUM_TO_CYTOSOL_TRANSPORT | 21 | −0.347 | −1.104 | 27 |
ES: Enrichment Score; NES: Normalized Enrichment Score.