Table 5.
Comparison of cytoskeletal and presynaptic related gene expression levels between genotypes and treatments
Gene | Mmu† | 2N+ fold of 2N‡ | Ts fold of 2N | Ts+ fold of 2N | Ts+ fold of Ts |
---|---|---|---|---|---|
Cytoskeletal | |||||
Gabarap | 11 | 8.87** | 8.16** | 2.05 | 0.25** |
Tubb4b | 2 | 3.29** | 3.01** | 0.81 | 0.27** |
Nefh | 11 | 1.16 | 1.62 | 0.88 | 0.54** |
Dbn1 | 13 | 1.05 | 1.13 | 2.13** | 1.88** |
Sncg | 14 | 1.06 | 1.11 | 4.94** | 4.46** |
Dcx | X | 0.97 | 1.02 | 2.22** | 2.17** |
Cav2 | 6 | 0.93 | 0.92 | 1.37 | 1.48* |
Cav3 | 6 | 0.87 | 0.84 | 1.46** | 1.74** |
Dync1h1 | 12 | 0.86 | 0.37* | 0.77 | 2.08* |
Synpo | 18 | 0.05** | 0.06** | 0.07** | 1.06 |
Presynaptic | |||||
Syngr1 | 15 | 0.89 | 14.64** | 0.99 | 0.07** |
Snap29 | 8 | 2.21** | 1.13 | 1.38 | 1.22 |
Bsn | 9 | 0.91 | 1.00 | 0.65 | 0.66* |
Snca | 6 | 0.26** | 0.33** | 0.61* | 1.87 |
Mus musculus chromosome using build Grmc38, NT denotes not triplicated;
2N, disomic mice, Ts, Ts65Dn,
, maternal choline supplementation;
, p < 0.005;
, p < 0.01