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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Stroke. 2019 Aug 9;50(10):2865–2874. doi: 10.1161/STROKEAHA.119.025371

Figure 1. MiR-126 measurement in vivo and in vitro.

Figure 1.

(A-B) Compared to non-DM stroke mice, T2DM-stroke mice exhibit significantly decreased serum and brain tissue miR-126 expression. Treatment of T2DM-stroke mice with EC-Exo significantly increases serum and brain tissue miR-126 expression. Loss of miR-126 in EC-Exo attanuates EC-Exo induced increase in seruma nd brain miR-126 expression. (C-D) ECs and EC-Exo contain high levels of miR-126 compared to other cell types or exosomes derived from other types of cells, respectively.