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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Stroke. 2019 Aug 9;50(10):2865–2874. doi: 10.1161/STROKEAHA.119.025371

Figure 5. EC-Exo promotes M2 macrophage poliraztion in T2DM-stroke mice.

Figure 5.

EC-Exo treatment of T2DM-stroke mice significantly decreases ED1 positive M1 macrophages (A) while increasing CD163 positive M2 macrophages (B) in the IBZ (cortex, corpus callosum and striatum) of T2DM-stroke mice. Loss of miR-126 in EC-Exo attenuates EC-Exo induced M2 macrophage polarization.