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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Gastroenterology. 2019 Jun 5;157(4):1123–1137.e22. doi: 10.1053/j.gastro.2019.06.001

Figure 3. BaseScope in-situ RNA detection of mutant KRAS in FFPE IPMN tissues.

Figure 3.

A. Hematoxylin stain of low-grade IPMN sample IPC09 B. B-C. Representative image of Area 1 probed for either KRAS p.G12D (B) or KRAS p.G12V (C). D-E. Representative image of Area 2 probed for either KRAS p.G12D (D) or KRAS p.G12V (E). F-G. Representative image of Area 3 probed for either KRAS p.G12D (F) or KRAS p.G12V (G). H. Hematoxylin stain of IPC09 B overlaid with green, indicating areas of positive staining for KRAS p.G12D or red, indicating areas of positive staining for KRAS p.G12V. Dark red dots designate positive signal (black arrows point to representative cells with positive staining). Nuclei were counterstained with hematoxylin. A and H = Magnification 0.5X. B-G = Magnification 15X.