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. 2019 Sep 23;9:13677. doi: 10.1038/s41598-019-50216-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Viability of E. coli (A) and B. subtilis (B) and their ppGpp-null variants is differently affected by SFN or PEITC. Results are shown as the mean ± SD values from 3 experiments. Cultures were treated at 37 °C for 24 h with SFN or PEITC at indicated concentrations. Bactericidal activity was defined as a reduction of 99.9% (≥3 log10) of the total number of CFU mL^-1 in the original inoculum and marked as dashed line on plots.