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. 2019 Sep 23;9:13678. doi: 10.1038/s41598-019-50134-y

Table 6.

Rats pain reaction time after topically applied with normal saline (10 mL/kg), pure Eucalyptus essential oil (500 mg/kg), and Eucalyptus essential oil-micellar nanoparticle (100 mg/kg).

Treatments aReaction time (s)
0 3 15 30 45 60

Normal saline

(10 mL/kg)

22.5 ± 3.95 19.0 ± 2.95 24.0 ± 6.15 24.0 ± 3.61 17.3 ± 2.25 15.8 ± 3.02

Pure Eucalyptus essential oil

(500 mg/kg)

33.5 ± 0.70 34.0 ± 2.25 29.3 ± 3.3 31.5 ± 2.18 28.8 ± 2.05 34.3 ± 3.05
Eucalyptus essential oil-micellar nanoparticle (100 mg/kg) 35.0 ± 4.10 36.0 ± 2.45 34.8 ± 3.45 37.0 ± 3.50 30.3 ± 3.55 40.8 ± 2.7

aMean of rat’s pain reaction time.