Table 2.
The AUC, cutoff value, sensitivity, and specificity of parameters for the diagnosis of malignant pleural effusion
| Parameters | AUC | 95% confidence interval | P | Cutoff | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|---|---|
| pPOSTN (ng/mL) | 0.735 | 0.622‐0.847 | 0.000 | 403.4 | 97.73 | 52.50 |
| sPOSTN (ng/mL) | 0.687 | 0.572‐0.801 | 0.004 | 302.0 | 47.73 | 87.50 |
| pADA (U/L) | 0.818 | 0.715‐0.922 | 0.000 | 26.5 | 95.45 | 70.00 |
| pLDH (U/L) | 0.541 | 0.332‐0.586 | 0.522 | 550 | 62.79 | 52.50 |
| pRBC (103/μL) | 0.650 | 0.529‐0.772 | 0.019 | 3.76 | 63.64 | 70.00 |
| pCA125 (U/mL) | 0.711 | 0.599‐0.823 | 0.001 | 2180.3 | 47.73 | 95.50 |
| pCA199 (U/mL) | 0.699 | 0.581‐0.818 | 0.002 | 13.5 | 45.45 | 97.50 |
| sCRP (mg/L) | 0.803 | 0.705‐0.900 | 0.000 | 36.0 | 81.82 | 74.36 |
| pGLU (mmol/L) | 0.632 | 0.510‐0.754 | 0.040 | 6.62 | 52.27 | 77.50 |
| pWBC (103/μL) | 0.645 | 0.522‐0.767 | 0.024 | 1.79 | 68.18 | 62.50 |
| sPOSTN/pADA | 0.844 | 0.749‐0.940 | 0.000 | 11.86 | 86.36 | 80.00 |
| pCA199/pADA | 0.847 | 0.765‐0.928 | 0.000 | 0.244 | 72.73 | 85.00 |
| pCA199/pPOSTN | 0.841 | 0.758‐0.924 | 0.000 | 0.015 | 88.64 | 65.00 |
| sPOSTN/pADA+pCA199/pADA+pCA199/pPOSTN | 0.912 | 0.850‐0.974 | 0.000 | 0.317 | 95.45 | 77.50 |