Table 5.

Correlation of 10 candidate miRNAs with disease activity in the qPCR validation

Parameters	ESR	CRP	DAS28
miR‐192‐5p
Correlation coefficient R	0.146	−0.042	0.115
P value	0.164	0.690	0.276
miR‐146a‐5p
Correlation coefficient R	0.231	0.204	0.065
P value	0.027	0.051	0.541
miR‐19b‐3p
Correlation coefficient R	−0.134	‐0.095	−0.099
P value	0.204	0.368	0.349
miR‐320c
Correlation coefficient R	‐0.068	−0.161	0.119
P value	0.521	0.125	0.257
miR‐335‐5p
Correlation coefficient R	‐0.140	−0.008	−0.226
P value	0.185	0.943	0.030
miR‐149‐3p
Correlation coefficient R	‐0.040	0.041	0.068
P value	0.705	0.701	0.522
miR‐766‐3p
Correlation coefficient R	−0.064	−0.028	−0.011
P value	0.546	0.790	0.920
let‐7a‐5p
Correlation coefficient R	0.092	0.039	0.261
P value	0.383	0.711	0.012
miR‐24‐3p
Correlation coefficient R	0.051	−0.089	−0.115
P value	0.631	0.397	0.276
miR‐1226‐5p
Correlation coefficient R	0.129	0.240	0.057
P value	0.221	0.021	0.591

Correlation was determined by Spearman's test. P < 0.05 was considered significant.

Abbreviations: CRP, C‐reactive protein; DAS28, disease activity score in 28 joints; ESR, erythrocyte sedimentation rate; miRNA, microRNA.