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. 2018 Jan 31;10(3):189–201. doi: 10.1159/000486321

Fig. 9.

Fig. 9

Cytokine responses in macrophage culture supernatant from FcGRIIb−/− (a–c) or wild-type (FcGRIIb+/+) (d–f) mice after activation with (1→3)-β-D-glucan (BG) alone at different doses (100 μg/mL, ◇; 10 μg/mL, ◻; 1 μg/mL, ⚪), endotoxin (10 ng/mL LPS) alone (gray triangle), and BG + LPS (100 μg/mL BG + 10 ng/mL LPS, ◆; 10 μg/mL BG + 10 ng/mL LPS, ◼; 1 μg/mL BG + 10 ng/mL LPS, ⚫). Separate, triplicate experiments were performed. g–i The area under the curve (AUC) of cytokine responses in the macrophage culture supernatant (in vitro) from both strains with 10 ng/mL LPS alone and LPS with different doses of BG. BG 10, 10 μg/mL BG; BG 100, 100 μg/mL BG. * p < 0.05 versus LPS 10 ng/mL at the same time point.