Table 1.
Baseline characteristics of AIS patients and controls
| Items | AIS patients (N = 160) | Controls (N = 160) | P value |
|---|---|---|---|
| Age (y), mean ± SD | 62.5 ± 12.9 | 60.6 ± 10.7 | 0.160 |
| Gender, No. (%) | |||
| Male | 109 (68.1) | 114 (71.2) | 0.543 |
| Female | 51 (31.9) | 46 (28.8) | |
| BMI (kg/m2), mean ± SD | 24.7 ± 2.9 | 24.2 ± 2.8 | 0.087 |
| Smoke, No. (%) | 78 (48.8) | 83 (51.9) | 0.576 |
| Chronic complications, No. (%) | |||
| Hypertension | 145 (90.6) | 135 (84.4) | 0.091 |
| Diabetes mellitus | 37 (23.1) | 25 (15.6) | 0.155 |
| Hyperlipidemia | 77 (48.1) | 63 (39.4) | 0.115 |
| Hyperuricemia | 47 (29.4) | 44 (27.5) | 0.710 |
| Chronic kidney disease | 26 (16.3) | 19 (11.9) | 0.260 |
| NIHSS score, mean ± SD | 8.3 ± 3.4 | ‐ | ‐ |
| CRP (mg/L), median (IQR) | 35.5 (27.3‐49.4) | ‐ | ‐ |
| TNF‐α (pg/mL), median (IQR) | 78.7 (56.5‐124.5) | ‐ | ‐ |
| IL‐1β (pg/mL), median (IQR) | 6.7 (4.5‐9.2) | ‐ | ‐ |
| IL‐6 (pg/mL), median (IQR) | 62.3 (49.9‐81.7) | ‐ | ‐ |
| IL‐8 (pg/mL), median (IQR) | 66.8 (49.3‐97.2) | ‐ | ‐ |
| IL‐10 (pg/mL), median (IQR) | 16.1 (11.2‐23.4) | ‐ | ‐ |
| IL‐17 (pg/mL), median (IQR) | 128.7 (82.1‐166.1) | ‐ | ‐ |
| IL‐22 (pg/mL), median (IQR) | 75.1 (53.6‐108.2) | ‐ | ‐ |
Comparisons between groups were determined by t test or chi‐square test. P value < 0.05 was considered significant.
Abbreviations: AIS, acute ischemic stroke; BMI, body mass index; CRP, C‐reactive protein; IL, interleukinIQR, interquartile range; NIHSS, National Institutes of Health stroke scale; SD, standard deviation; TNF‐α, tumor necrosis factor‐α.