Table 2. MIC of 34 ESBL-producing S. flexneri and corresponding conjugon (μg/ml).
Antimicrobial agents | Range of MIC | Crit. conc. | MIC of 34 ESBLs- producing S. flexneri (quantity) | MIC of 34 conjugon (quantity) | ||
---|---|---|---|---|---|---|
CTX-M-14type(9) | CTX-M-15type(25) | CTX-M-14type(9) | CTX-M-15type(25) | |||
Ampicillin | 0.016–256 | 16 | >256(9) | >256(25) | >256(9) | >256(25) |
Cefotaxime | 0.016–256 | 2 | 32(7), >256(2) | >256(25) | 16(2), 32(7) | >256(25) |
Ceftazidime | 0.016–256 | 8 | 1(7), 2(2) | 16(2), 32(23) | 0.5(1), 1(1), 2(7) | 8(2), 16(23) |
Cefoxitin | 0.016–256 | 16 | 2(2), 4(7) | 2(2), 4(23) | 2(1), 4(8) | 2(1), 4(24) |
Cefepime | 0.016–256 | 16 | 4(5), 8(4) | 64(8), 128(9), 256(8) | 1(3), 2(4), 4(2) | 16(8), 64(14), 256(3) |
Imipenem | 0.06–32 | 8 | 0.25(7), 0.5(2) | 0.25(23), 0.5(2) | 0.125(7), 0.25(2) | <0.06(10), 0.125(15) |
Ciprofloxacin | 0.02–32 | 2 | 0.125(2), 4(7) | 0.25(20), 4(5) | <0.02(9) | <0.02(25) |
Gentamicin | 0.016–128 | 8 | 1(5), 2(3), 32(1) | 1(21), 2(4) | 0.25(8), 0.5(1), 8(1) | 0.25(15), 0.5(6), 1(4) |
Chloramphenicol | 0.016–256 | 16 | 128(3), >256(6) | 64(11), 128(5), 256(9) | 4(5), 8(4) | 4(23), 8(2) |
Tetracycline | 0.016–256 | 8 | 128(1), 256(8) | 128(2), 256(23) | 1(8), 2(1) | 1(23), 128(2) |
Sulfamethoxazole | 2–1024 | 64 | >1024(9) | >1024(25) | 4(2), 8(7) | 4(7), 8(16), 16(2) |
Trimethoprim | 0.125–64 | 4 | >64(9) | >64(25) | <0.125(9) | <0.125(25) |