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. 2019 Sep 24;39(9):BSR20191741. doi: 10.1042/BSR20191741

Table 2. MIC of 34 ESBL-producing S. flexneri and corresponding conjugon (μg/ml).

Antimicrobial agents Range of MIC Crit. conc. MIC of 34 ESBLs- producing S. flexneri (quantity) MIC of 34 conjugon (quantity)
CTX-M-14type(9) CTX-M-15type(25) CTX-M-14type(9) CTX-M-15type(25)
Ampicillin 0.016–256 16 >256(9) >256(25) >256(9) >256(25)
Cefotaxime 0.016–256 2 32(7), >256(2) >256(25) 16(2), 32(7) >256(25)
Ceftazidime 0.016–256 8 1(7), 2(2) 16(2), 32(23) 0.5(1), 1(1), 2(7) 8(2), 16(23)
Cefoxitin 0.016–256 16 2(2), 4(7) 2(2), 4(23) 2(1), 4(8) 2(1), 4(24)
Cefepime 0.016–256 16 4(5), 8(4) 64(8), 128(9), 256(8) 1(3), 2(4), 4(2) 16(8), 64(14), 256(3)
Imipenem 0.06–32 8 0.25(7), 0.5(2) 0.25(23), 0.5(2) 0.125(7), 0.25(2) <0.06(10), 0.125(15)
Ciprofloxacin 0.02–32 2 0.125(2), 4(7) 0.25(20), 4(5) <0.02(9) <0.02(25)
Gentamicin 0.016–128 8 1(5), 2(3), 32(1) 1(21), 2(4) 0.25(8), 0.5(1), 8(1) 0.25(15), 0.5(6), 1(4)
Chloramphenicol 0.016–256 16 128(3), >256(6) 64(11), 128(5), 256(9) 4(5), 8(4) 4(23), 8(2)
Tetracycline 0.016–256 8 128(1), 256(8) 128(2), 256(23) 1(8), 2(1) 1(23), 128(2)
Sulfamethoxazole 2–1024 64 >1024(9) >1024(25) 4(2), 8(7) 4(7), 8(16), 16(2)
Trimethoprim 0.125–64 4 >64(9) >64(25) <0.125(9) <0.125(25)