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. 2019 Sep 12;2019:6523837. doi: 10.1155/2019/6523837

Table 2.

Results of overall and subgroup analyses for gene polymorphisms (rs28362491 and rs2233406).

rs28362491 No D versus I DD versus II DI versus II DD+DI versus II DD versus DI+II
OR 95% CI P (z) OR (95% CI) P (z) OR (95% CI) P (z) OR (95% CI) P (z) OR (95% CI) P (z)
Overall 9 0.89 0.79-1.00 0.059 0.76 0.60-0.97 0.026 0.95 0.82-1.08 0.419 0.89 0.76-1.05 0.165 0.80 0.68-0.95 0.010
PCR-RFLP 2 1.04 0.89-1.22 0.630 0.96 0.65-1.40 0.813 1.17 0.93-1.48 0.179 1.13 0.91-1.41 0.274 0.88 0.62-1.26 0.495
PCR-PAGE 2 0.74 0.61-0.91 0.004 0.57 0.38-0.85 0.007 0.73 0.53-1.02 0.063 0.67 0.49-0.92 0.012 0.69 0.49-0.98 0.039
TaqMan 3 0.79 0.69-0.91 0.001 0.61 0.45-0.83 0.002 0.83 0.69-1.00 0.047 0.75 0.60-0.94 0.014 0.70 0.60-0.83 <0.001
OC 3 0.86 0.58-1.27 0.457 0.73 0.32-1.65 0.446 0.82 0.56-1.20 0.314 0.79 0.46-1.33 0.369 0.84 0.49-1.46 0.543
HNC 2 1.04 0.88-1.22 0.630 0.96 0.65-1.40 0.813 1.17 0.93-1.48 0.179 1.13 0.91-1.41 0.274 0.88 0.62-1.26 0.495
NC 4 0.87 0.78-0.96 0.007 0.75 0.62-0.90 0.002 0.94 0.81-1.09 0.400 0.87 0.74-1.02 0.096 0.78 0.68-0.89 <0.001

rs2233406 No T versus C TT versus CC TC versus CC TT+TC versus CC TT versus CC+TC
OR 95% CI P (z) OR (95% CI) P (z) OR (95% CI) P (z) OR (95% CI) P (z) OR (95% CI) P (z)
Overall 4 1.13 0.90-1.42 0.296 1.51 0.99-2.30 0.058 1.08 0.85-1.39 0.523 1.12 0.86-1.44 0.399 1.50 0.98-2.29 0.061
TaqMan 2 1.25 0.72-2.16 0.431 1.68 0.93-3.04 0.084 1.19 0.66-2.12 0.565 1.23 0.68-2.23 0.497 1.67 0.92-3.02 0.089
OC 2 1.39 0.97-1.98 0.074 1.92 0.93-3.98 0.080 1.36 0.99-1.88 0.059 1.40 0.98-2.00 0.062 1.81 0.87-3.75 0.111
NC 2 0.96 0.83-1.10 0.520 1.33 0.79-2.24 0.290 0.90 0.77-1.05 0.180 0.92 0.79-1.07 0.296 1.36 0.81-2.29 0.251