Table 3.
Variables | OR (95% CI) | P a | Powerb | Prior probability | ||||
---|---|---|---|---|---|---|---|---|
0.25 | 0.1 | 0.01 | 0.001 | 0.0001 | ||||
D versus I | ||||||||
PCR-PAGE | 0.74 (0.61-0.91) | 0.004 | 0.839 | 0.015 | 0.044 | 0.338 | 0.837 | 0.981 |
TaqMan | 0.79 (0.69-0.91) | 0.001 | 0.991 | 0.003 | 0.010 | 0.098 | 0.523 | 0.916 |
NC | 0.87 (0.78-0.96) | 0.006 | 1.000 | 0.016 | 0.048 | 0.355 | 0.847 | 0.982 |
| ||||||||
DD versus II | ||||||||
Overall | 0.76 (0.60-0.97) | 0.027 | 0.854 | 0.088 | 0.225 | 0.761 | 0.970 | 0.997 |
PCR-PAGE | 0.57 (0.38-0.85) | 0.006 | 0.221 | 0.073 | 0.192 | 0.723 | 0.963 | 0.996 |
TaqMan | 0.61 (0.45-0.83) | 0.002 | 0.286 | 0.017 | 0.050 | 0.364 | 0.853 | 0.983 |
NC | 0.75 (0.62-0.90) | 0.002 | 0.897 | 0.007 | 0.020 | 0.180 | 0.688 | 0.957 |
| ||||||||
DI versus II | ||||||||
TaqMan | 0.83 (0.69-1.00) | 0.050 | 0.989 | 0.132 | 0.313 | 0.833 | 0.981 | 0.998 |
| ||||||||
DD+DI versus II | ||||||||
PCR-PAGE | 0.67 (0.49-0.92) | 0.013 | 0.512 | 0.072 | 0.190 | 0.720 | 0.963 | 0.996 |
TaqMan | 0.75 (0.60-0.94) | 0.013 | 0.847 | 0.042 | 0.117 | 0.594 | 0.937 | 0.993 |
| ||||||||
DD versus DI+II | ||||||||
Overall | 0.80 (0.68-0.95) | 0.011 | 0.981 | 0.032 | 0.091 | 0.524 | 0.918 | 0.991 |
PCR-PAGE | 0.69 (0.49-0.98) | 0.038 | 0.576 | 0.166 | 0.374 | 0.868 | 0.985 | 0.998 |
TaqMan | 0.70 (0.60-0.83) | 0.00004 | 0.713 | <0.001 | 0.001 | 0.006 | 0.054 | 0.363 |
NC | 0.78 (0.68-0.89) | 0.0002 | 0.990 | 0.001 | 0.002 | 0.022 | 0.184 | 0.693 |
aChi-square test was adopted to calculate the genotype frequency distributions. bStatistical power was calculated using the number of observations in the subgroup and the OR and P values in this table.