Table 1.
Baseline patient characteristics.
| Characteristics | Control group (n = 40) | All patients (n = 127) | Survivors (n = 87) | Nonsurvivors (n = 40) | p value |
|---|---|---|---|---|---|
| Age (years) | 63 (60-66) | 66 (54-76) | 64 (52-75) | 70 (60-80) | 0.050 |
| Sex (male/female) | 18/22 | 93/34 | 63/24 | 30/10 | 0.761 |
| APACHE II score | — | 19 (15-25) | 17 (13-22) | 25 (17-29) | 0.001 |
| ICU stay (day) | — | 19 (8-28) | 25 (15-28) | 8 (5-13) | 0.001 |
| Temperature | — | 38.2 (37.7-38.7) | 38.2 (37.8-38.2) | 38.7 (37.1-38.7) | 0.634 |
| Heart rate | — | 103 (94-117) | 102 (90-115) | 110 (99-120) | 0.045 |
| Respiration rate | — | 23 (20-27) | 22 (20-26) | 25 (17.5-28.75) | 0.002 |
| MAP (mmHg) | — | 80 (72.3-91.7) | 82 (76-95) | 75 (67-85) | 0.007 |
| WBC, 109/L | — | 12.8 (9.7-17.8) | 12 (9.21-15.3) | 16.6 (11.7-23.2) | 0.001 |
| PMN, 109/L | — | 11.2 (8.5-15.5) | 10.2 (7.9-13.4) | 14.7 (10.7-22) | 0.001 |
| PaO2/FiO2 | — | 177 (123-225) | 194 (153-242) | 110.5 (83-201.5) | 0.001 |
| Lactate (mmol/l) | — | 1.7 (1.4-2.3) | 1.61 (1.4-2.1) | 2.1 (1.6-3.8) | 0.003 |
| PCT (ng/ml) | — | 1.43 (0.33-10.91) | 0.97 (0.29-8.55) | 3.8 (0.85-12.6) | 0.045 |
| Calreticulin (pg/ml) | 240 (113-283) | 418 (177-196) | 333 (107-129) | 899 (354-450) | 0.003 |
Data are expressed as medians (interquartile range). APACHE II score: Acute Physiology and Chronic Health Evaluation score II; ICU: intensive care unit; MAP: mean arterial pressure; WBC: white blood cell; PMN: neutrophils; PCT: procalcitonin.