Daniels 1990 LES.

Methods	Case‐control study (clinic‐based)
Participants	Cases: children aged < 5 years who presented to the participating health facilities with diarrhoea, n = 803 (after excluding 3), 43.5% aged < 12 months, 48.8% girls. Controls: the same age range who reported with either respiratory infections or trauma, but without diarrhoea. Children also had to: be accompanied by a parent or guardian who had been responsible for the child for the previous 3 months, be living in a HH within Mohale's Hoek district, have no congenital abnormality or chronic illness, and the accompanying adult had to consent to his or her child's inclusion in the study. n = 810 (after excluding 4). 54.6% < 12 months, 52.4% girls.
Interventions	Risk factor of interest: child faeces disposed in latrine vs not (no usable data, data reported for cases and controls jointly).
Outcomes	Diarrhoea: as defined by the mother, with ≥ 3 loose or watery stools in previous 24 hours
Notes	Location: 4 health facilities in rural Mohale's Hoek district, Lesotho Length of recruitment: 6 months (8 December 1987 to 6 June 1988) Publication status: journal
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	NA
Allocation concealment (selection bias)	Unclear risk	NA
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	NA
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	NA
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	NA
Selective reporting (reporting bias)	Unclear risk	NA
Other bias	Unclear risk	NA
Similarity of baseline outcome measurements	Unclear risk	NA
Similarity of baseline characteristics	Unclear risk	NA
Adequate allocation of intervention concealment during the study	Unclear risk	NA
Adequate protection against contamination	Unclear risk	NA
Confounders adequately adjusted for in analysis/design	Unclear risk	NA
Recruitment bias	Unclear risk	NA
Baseline imbalance	Unclear risk	NA
Loss of clusters	Unclear risk	NA
Incorrect analysis	Unclear risk	NA