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. 2019 Aug 14;18(4):4064–4073. doi: 10.3892/ol.2019.10741

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — miR-361 induces cell apoptosis in resistant HCT116 and HT29 cells. Annexin V staining of resistant miR-361-overexpressing (A) HCT116 and (B) HT29 cells. Q1: Dead cells, Q2: Late apoptotic cells, Q3: Living cells, Q4: Early apoptotic cells. The histogram indicated the percentage of early, late and total apoptotic cells with different concentrations of 5-FU. The total apoptotic cells include early and late apoptotic cells (n=3, **P<0.01 vs. NC cells). miR, microRNA; 5-FU, 5-fluorouracil; NC, negative control; Res, resistant.