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. 2019 Aug 22;18(4):4308–4316. doi: 10.3892/ol.2019.10769

Figure 1.

Figure 1.

DZNep reduces proliferation and colony formation of BGC-823 cells. (A) Compared with cells in the control group, cells in the DZNep group became thin and long, and exhibited a thread-like shape with a small circular terminal, and the arrangement of the cells became loose (magnification, ×200 and ×400). (B) In the CCK-8 assay, the absorbance of the DZNep group was significantly lower compared with that of the control group at 6 and 48 h. *P<0.05, **P<0.01 vs. respective DZNep group. (C) The number of colonies in the DZNep group was significantly lower compared with that in the control group at 5 and 7 days. *P<0.05, **P<0.01 vs. respective control group. CCK-8, Cell Counting kit-8; DZNep, 3-deazaneplanocin A; OD, optical density.