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miR-873 could directly bind to 3′UTR of ZEB1 mRNA. (A) Sequence alignment of miR-873 and potential binding sites on 3′UTR of ZEB1 mRNA were presented. (B) Transfection of miR-873 mimics, but not miR-NC mimics, reduced the luciferase activity of 293 cells transfected with pGL3-ZEB1 3′UTR-WT. ***P<0.0001 vs. miR-NC mimics. UTR, untranslated region; ZEB1, zinc finger E-box binding homeobox 1; WT, wild type; Mut, mutant; miR, microRNA.
