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. 2019 Aug 1;18(4):3837–3844. doi: 10.3892/ol.2019.10697

Figure 5.

Figure 5.

Overexpression of miR-873 or silencing of ZEB1 reverses gemcitabine resistance of MDA-MB-231GEMr cells. (A) Overexpression of miR-873 by transfection of miR-873 mimics reversed gemcitabine resistance of MDA-MB-231GEMr cells. *P<0.05 vs. miR-NC mimics. (B) ZEB1 protein level was decreased by transfection of ZEB1 siRNA1 or ZEB1 siRNA2. (C) Silencing of ZEB1 by transfection of ZEB1 siRNA reversed gemcitabine resistance of MDA-MB-231GEMr cells. *P<0.05; **P<0.01 vs. control siRNA. ZEB1, Zinc finger E-box binding homeobox 1; siRNA, small interfering RNA; NC, negative control; miR, microRNA.