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. 2019 Sep 12;2019:8768164. doi: 10.1155/2019/8768164

Figure 4.

Figure 4

Upregulation of Arsb reverses the effects of miR-154-5p on cardiomyocyte hypertrophy and apoptosis. (a) Expression of markers of cardiac hypertrophy in cardiomyocytes transfected with scramble, si-Arsb, as measured using real-time PCR (n = 3). (b) Western blot images showing the levels of Arsb, cleaved caspase-3, and caspase-3 in cardiomyocytes subjected to different treatments (n = 3). (c) Expression of markers of cardiac hypertrophy in cardiomyocytes transfected with NC, miR-154-5p, miR-154-5p+vector, and miR-154-5p+Arsb, as measured using real-time PCR (n = 3). (d) Western blot images showing the levels of Arsb, cleaved caspase-3, and caspase-3 in cardiomyocytes subjected to different treatments (n = 3). (e, f) Western blot images showing the levels of the p-JNK, JNK, p-p38, p38, p-STAT3, and STAT3 proteins in the Con, AngII, AngII+vector, and AngII+Arsb groups (n = 3) and in the NC, miR-154-p, miR-154-5p+vector, and miR-154-5p+Arsb groups (n = 3).