Table 2.
The ten differentially expressed genes in IgAN patients and healthy control
| Gene symbol | Gene name | P value | Fold_change |
|---|---|---|---|
| Downregulated | |||
| GRPEL1 | Proteasome subunit, beta type, 10 | 3.49 × 10−5 | 2.88 |
| OAT | Poly (ADP-ribose) polymerase family, member 12 | 4.82 × 10−5 | 2.63 |
| TFDP1 | MMS19 nucleotide excision repair homolog (S. cerevisiae) | 8.77 × 10−5 | 2.98 |
| SLC25A24 | Phosphopantothenoylcysteine decarboxylase | 1.33 × 10−4 | 1.07 |
| PPP1R2 | Uncharacterized protein DKFZp586I1420 | 1.79 × 10−4 | 2.09 |
| DDX21 | Dynein, cytoplasmic 1, heavy chain 1 | 1.97 × 10−4 | 2.30 |
| MBD2 | Focadhesin | 2.20 × 10−4 | 3.10 |
| MAPRE1 | Zinc finger protein 22 | 2.68 × 10−4 | 3.81 |
| CXCR4 | Exostosin-like glycosyltransferase 2 | 3.59 × 10−4 | 3.22 |
| IL1A | KIAA0513 | 3.63 × 10−4 | 3.26 |
| Upregulated | |||
| DOK3 | Docking protein 3 | 3.97 × 10−6 | 1.97 |
| REEP4 | Receptor accessory protein 4 | 9.99 × 10−6 | 2.21 |
| MRPS18A | Mitochondrial ribosomal protein S18A | 3.99 × 10−5 | 2.96 |
| DEF8 | Differentially expressed in FDCP 8 homolog | 8.24 × 10−5 | 1.48 |
| OXCT2 | 3-oxoacid CoA-transferase 2 | 2.19 × 10−4 | 1.74 |
| MAN2B1 | Mannosidase alpha class 2B member 1 | 3.26 × 10−4 | 3.46 |
| LRP3 | LDL receptor related protein 3 | 5.97 × 10−4 | 1.99 |
| EDC4 | Enhancer of mRNA decapping 4 | 7.97 × 10−4 | 2.17 |
| RAB23 | RAB23, member RAS oncogene family | 8.48 × 10−4 | 1.88 |
| COX4I1 | Cytochrome c oxidase subunit 4I1 | 8.57 × 10−4 | 3.64 |