Fig. 6.

TUFT1-knockdown TNBC cells are more sensitive to taxotere in vivo. a scr-shRNA- and TUFT1-shRNA-MDA-MB-231 cells were injected into nude mice as described in the Materials and Methods. The tumor volumes were measured following treatment with or without Taxotere (n = 5). Representative images showing tumor formed in nude mice after injection with scr-shRNA- or TUFT1-shRNA cells and IHC staining of TUFT1 in tumor tissues (scale bars, ×400). b, c Tumour volumes in four groups. The arrows showed the time of Taxotere injection. Results are presented as mean ± SD. The statistical significance was assessed by student’s t-test; *p < 0.05