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. 2019 Sep 24;2019(9):CD012177. doi: 10.1002/14651858.CD012177.pub2

Walker 2014.

Methods Paired cluster‐randomised trial
Participants Who: Interprofessional teams at 24 study hospitals
Number: 450 physicians and nurses
Proportion of eligible staff participating: 6.4 to 31.6% of eligible staff trained, mean participation rate 20.5%. 3228 were eligible.
Interventions Intervention description: PRONTO obstetric emergency training, which is largely interactive using a low‐technology hybrid simulator
Control: No intervention
Location: Unclear
Delivered by: PRONTO trainers
Length: 24 hours of training; 2 days followed by 1 day
Duration: Single intervention
Outcomes Outcomes: Perinatal mortality, neonatal mortality, achievement of strategic planning goals
Follow‐up: 3 years
Population studied Description: Hospital‐based neonatal and maternal morbidity and mortality at the study sites
Number: 58,837 deliveries and 641 births observed, deliveries at study sites.
Funding Source Mexican National Institute of Women (INMUJERES), the State Secretary for Women in the states of Chiapas and Mexico, Bill and Melinda Gates Foundation, and the Laerdel Foundation
Study Setting 24 community hospitals in Mexico
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk No description of how randomised, and 4 hospitals not randomised.
Allocation concealment (selection bias) Unclear risk Not discussed
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Not discussed, but not possible to blind participants
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not discussed
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Not discussed
Selective reporting (reporting bias) High risk Original primary and secondary outcomes could not all be reported due to rarity. This was made clear and justified.
Other bias High risk In 2 of the pairs, the local ministry of health selected the intervention hospitals rather than them being randomised. 11 of the original hospitals dropped out for a variety of reasons and were replaced by 11 similar sites.