Fig. 3.

BDNF regulation of LH behavior: long-term effects and multiple infusions. The LH paradigm was conducted as described in Materials and Methods, except conditioned avoidance testing was conducted 10 d after BDNF infusion into the dentate gyrus (left) or 3 d after infusions at three different rostrocaudal levels of dentate gyrus (right). The results are expressed as mean ± SEM. The number of animals is listed under each column. *p < 0.05; **p < 0.01; ***p < 0.001 when compared with saline-injected controls (Student's t test). Left top,F_(1,12) = 4.172; p= 0.0013; left bottom,F_(1,12) = 4.022; p= 0.0017; right top,F_(1,10) = 4.824; p= 0.0007; right bottom,F_(1,10) = 2.853; p= 0.0172.