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BDNF immunohistochemistry after local infusion into the hippocampus. BDNF (0.25 or 1.0 μg) was infused into the dentate gyrus, and BDNF immunolabeling was determined at the time points indicated. Representative sections are shown for each time point and dose of BDNF. Arrows indicate the sites of infusion. Similar effects were observed in three or four separate animals for each condition.
