Fig. 8.
Effects of electrical activity and target tissue interactions on the functional expression of KCa in LMNs developing in vivo. A, Inhibition of LMNs by in ovo application of muscimol or mecamylamine decreases KCa density, suggesting a role for activity in regulation of KCa. In contrast, in ovotreatment with the neuromuscular blocker d-tubocurarine significantly increased KCa density, consistent with a role for target tissue interactions in KCa regulation.B, Removal of target tissues reduced KCadensity in LMNs compared with sham-operated controls.#p < 0.05 versus vehicle;##p < 0.05 versus control.