Table 1.
Patient characteristics of cases evaluated for active caspase-3-like immunoreactivity
Case | Cause of death | Time to autopsy | HIV status | Neuropsych testing | Neuropathology |
---|---|---|---|---|---|
1 | Hepatic failure | 4 hr | HIV+ | Impaired | HIVE |
2 | Pneumonia | 24 hr | HIV+ | Impaired | HIVE |
3 | Pneumonia | 24 hr | HIV+ | Impaired | HIVE |
4 | Hepatic failure | 3 hr | HIV+ | Impaired | HIVE |
5 | Pneumonia | 16 hr | HIV+ | Impaired | HIVE |
6 | Pneumonia | 10 hr | HIV+ | Normal | None |
7 | Sepsis | 14 hr | HIV+ | Normal | None |
8 | Fungal sepsis | 24 hr | HIV+ | Normal | Fungal vasculitis |
9 | Hepatic failure | 24 hr | HIV− | Not available | Type II Alzheimer's gliosis |
10 | Hepatic failure | 7 hr | HIV− | Not available | None |
The age range was 33–55 years. There was no significant difference in mean age or time to autopsy between patients with HIVE and controls. The cause of death for each HAD–HIVE case was also represented in the control group. HIV+, HIV positive; HIV−, HIV negative.