Fig. 10.

dSlo is not modulated by activation of endogenous PKA. Whole-cell dSlo currents were elicited by 300 msec test pulses to +100 mV from a holding potential of −80 mV. Forskolin was applied directly to the bath solution at the arrows, after a stable recording of dSlo current was established. The normalized peak current and the activation time constant are plotted as a function of time, with (▪) or without (■) the addition of forskolin. There was no apparent difference in either the peak currents (A) or activation time constant (B) in the absence and presence of 50 μm forskolin.