Fig. 5.
Summary of the dose-dependent suppressions of EPSCs and IPSCs by WIN55,212-2 (WIN).A, Amplitudes of WIN55,212-2-sensitive IPSCs (open circles), WIN55,212-2-insensitive IPSCs (triangles), and EPSCs (closed circles) plotted against the concentration of WIN55,212-2. In each cell, current amplitudes in the presence of WIN55,212-2 were expressed as the percentages of the control values (dotted line) obtained before application of WIN55,212-2. Eachsymbol represents the average value from the indicatednumber of neuron pairs. B, Individual values of current amplitudes in the presence of 100 nm WIN55,212-2 for WIN55,212-2-sensitive IPSCs (open circles), WIN55,212-2-insensitive IPSCs (triangles), and EPSCs (closed circles).