Fig. 10.

Wild-type and Snca mutant mice show similar increases in locomotor activity in response to amphetamine. Injections of either saline or d-amphetamine were given at 30 min. Squares indicate spontaneous locomotor activity, circles indicate amphetamine-induced activity, open symbols represent the Sncamutant mice (n = 11), and closed symbols represent the wild-type mice (n = 11). The averages of total activity counts (light beam breaks) per 10 min interval are shown ± SEM. The mobile and static count time courses are similar, although reduced in magnitude to the total counts both with and without amphetamine.