Fig. 10.

Summary of phenotypic differences in the GluRδ2 knock-out mouse. In the wild-type mouse, territories by CFs (dark blue) and PFs (green) are well segregated along the proximal-to-distal axis of PC dendrites, being connected by a short intermediate segment with mixed CF–PF innervation (light blue). In the knock-out mouse, CFs produce numerous collaterals, which extend distally to spiny branchlets. CFs often exceed the innervating dendrites and jump to form ectopic synapses on adjacent spiny branchlets. Such aberrant jumping sometimes causes multiple innervation of a given PC by anterogradely labeled and unlabeled CFs.