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. 2002 Oct 1;22(19):8739–8747. doi: 10.1523/JNEUROSCI.22-19-08739.2002

Fig. 6.

Fig. 6.

Dynamics of habituation is modulated by the NO/cGMP system in the circuitry of a single AL. Fifteen minutes before habituation, groups of animals were injected (1 μl into the hemolymph) with PBS, caged NO (500 μm), and caged cGMP (500 μm), or with ODQ (500 μm), ODQ plus caged NO, and ODQ plus caged cGMP. For local NO or cGMP release, animals receive light flashes focused onto one AL followed by habituation of the flashed and the nonflashed side. The values represent the mean ± SEM of the number of stimuli needed to meet the habituation criterion for each side. Number of animals tested is indicated in the bars [nonflashed side: ANOVA,p < 0.0001; Scheffe's post hoctest, p < 0.004; groups injected with ODQ, ODQ plus caged NO, and ODQ plus caged cGMP differ from groups injected with PBS, caged NO, and caged cGMP; flashed side: ANOVA,p < 0.0001; * indicates significant differences between habituated and nonhabituated side (p< 0.002, paired t test)].