Skip to main content
. 2002 Oct 1;22(19):8691–8704. doi: 10.1523/JNEUROSCI.22-19-08691.2002

Fig. 8.

Fig. 8.

Effects of synaptic conductances and potassium leak current on network activity. Decrease of potassium leak current inPY and TC cells transformed SWS oscillations into persistent firing at frequency depending on PY–PY synaptic conductance. A, In the presence of the strongRE–TC–RE coupling the RE–TC network generated spontaneous spindles even during continuous firing in the PY–IN network.A1,gPY−PY = 0.15 μS, gRE−TC = 0.2 μS,gTC−RE = 0.4 μS. A2,gPY−PY = 0.09 μS, gRE−TC = 0.2 μS,gTC−RE = 0.4 μS. A3,gPY−PY = 0.09 μS, gRE−TC = 0.1 μS,gTC−RE = 0.2 μS. B, Input resistance of PY cells and frequency of spontaneous firing versus maximal conductances for AMPA-mediated PY–PY synapses (gKL = 0,gRE−TC = 0.1 μS, gTC−RE = 0.2 μS) and potassium leak channels (gPY−PY= 0.08 μS,gRE−TC = 0.1 μS, andgTC−RE = 0.2 μS).