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. 2002 Nov 15;22(22):9922–9931. doi: 10.1523/JNEUROSCI.22-22-09922.2002

Table 1.

Comparison of mIPSCav attributes in morphologically identified neurons of seizure-resistant, normal, and seizure-prone rat strains

Strain, cell type
Seizure-resistant Normal Seizure-prone
Pyramidal Nonpyramidal Pyramidal Nonpyramidal Pyramidal Nonpyramidal
Number of cells 15 12 15 9 15 12 41-b
τ1(msec) 1.7  ± 0.13* 1.6  ± 0.1 2.4  ± 0.2 2.1  ± 0.2 3.0  ± 0.7* 5.1  ± 0.51-165
τ2 (msec) 20.3  ± 1.01-165 21.0  ± 0.8 24.2  ± 2.5 24.3  ± 2.4 27.7  ± 3.4* 39.9  ± 5.21-165 26.6  ± 6.7
% τ11-a 40.0  ± 5.1 30.0  ± 2.9 40.0  ± 2.5 30.0  ± 6.7 40.0  ± 2.5 46.7  ± 4.5
Amplitude (pA) −57.3  ± 4.01-165 −59.8, 3.6* −44.6  ± 3.7 −51.7  ± 5.2 −39.7, 3.8 −34.0  ± 4.1* −29.4

Values are mean ± SEM.

F1-a

 Percentage of deactivation time course devoted to fastest time constant.

F1-b

 Neurons identified as having monoexponentially decaying mIPSCavs.

Significance with respect to neurons of the same morphology in normal rats:

*

p < 0.05;

F1-160: p < 0.01;

F1-165: p< 0.001.