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. 2002 Nov 15;22(22):9922–9931. doi: 10.1523/JNEUROSCI.22-22-09922.2002

Table 2.

Comparison of mIPSC attributes in morphologically identified neurons of seizure-resistant, normal, and seizure-prone rat strains

Strain, cell type
Seizure-resistant Normal Seizure-prone
Pyramidal Nonpyramidal Pyramidal Nonpyramidal Pyramidal Nonpyramidal
Number of cells 13 12 13 9 13 11
Monoexponential
 τ1 (msec) 11.6, 14.32-160 12.1, 13.02-160 14.4, 15.9 15.7, 17.1 17.1, 18.8**,*** 21.6, 23.4**,***
 Amplitude (pA) −39.9, 35.02-160 −39.0, 27.1* −32.7, 25.8 −35.9, 23.4 −26.3, 24.6**,*** −27.8, 17.0**,***
 Number of events 750 533 634 500 560 534
Biexponential
 τ1 (msec) 1.7, 0.8* 1.6, 0.7 2.3, 1.1 1.7, 0.8 2.6, 1.12-165 4.4, 1.5**,***
 τ2 (msec) 26.3, 9.82-160 25.8, 9.4 35.0, 12.9 31.5, 10.8 35.8, 12.62-165 51.6, 20.1**,***
 % τ1 42.4, 11.9 41.3, 11.7 42.9, 11.5 35.2, 9.9 43.6, 10.5 44.9, 10.12-160
Amplitude (pA) −74.1, 43.62-160 −60.3, 18.9 −49.3, 13.8 −56.0, 15.4 −43.1, 24.72-165 −36.2, 14.5**,***
Number of events 200 163 189 149 187 157

Values are median, interquartile range.

F2-a

 Percentage of deactivation time course devoted to fastest time constant.

Significance with respect to neurons of the same morphology in normal rats:

*

p <0.01;

F2-160: p<0.001.

Significance with respect to neurons of the same morphology in seizure-resistant rats:

F2-165: p ≪0.001.