Table 1.
Endogenous levels of AEA1-a | Endogenous levels of 2-AG1-a | PLD activity1-b | AMT activity1-c | FAAH activity1-d | Binding of AEA1-e | Binding of CP55,9401-f | |
---|---|---|---|---|---|---|---|
Naive | 250 ± 20 | 1250 ± 120 | 320 ± 32 | 90 ± 10 | 470 ± 50 | 150 ± 15 | 114 ± 11 |
6-OHDA lesioned | 750 ± 80* | 1300 ± 125 | 350 ± 35 | 35 ± 4* | 180 ± 20* | 167 ± 16 | 130 ± 12 |
Expressed as picomoles per milligram of protein.
Expressed as picomoles per minute per milligram of protein (substrate was 10 μm1,2-dioleoyl-3-phosphatidyl-[2-14C]ethanolamine).
Expressed as picomoles per minute per milligram of protein (substrate was 400 nm[3H]AEA).
Expressed as picomoles per minute per milligram of protein (substrate was 5 μm[3H]AEA).
Expressed as femtomoles per milligram of protein (ligand was 200 pm[3H]AEA).
Expressed as femtomoles per milligram of protein (ligand was 200 pm[3H]CP55,940).
p <0.01 compared with control (n= 4).