Table 2.
Age and inflammation-dependent AA amyloid deposition
| Age/treatment | SAA1 expression in brain | Amyloid deposition: number of deposits per section | Amyloid deposition: percentage of area occupied |
|---|---|---|---|
| 8 months | 100 ± 8% | 98 ± 17.9 | 0.84 ± 0.31% |
| 18 months | 115 ± 17% | 231 ± 67* | 2.21 ± 0.52%* |
| − Indomethecin | 98 ± 11% | 101 ± 13.6 | 0.92 ± 0.28% |
| + Indomethecin | 106 ± 15% | 8 ± 7.2* | 0.01 ± 0.09%* |
SAA expression is given in arbitrary units. Amyloid deposition indicates the percentage of area occupied by the amyloid material.
*
Indicates significant difference compared with untreated transgenic mice.