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. 2002 Jul 15;22(14):5910–5919. doi: 10.1523/JNEUROSCI.22-14-05910.2002

Fig. 6.

Fig. 6.

Reduction of brain injury in IL-18 KO mice compared with wild-type mice (wt). A, Infarction size was quantified in 10 coronal sections numbered from anterior to posterior levels. Infarction was expressed as loss of MAP-2 immunoreactivity in the ipsilateral hemisphere as a percentage of the contralateral hemisphere. Values are given as mean ± SEM. ***p < 0.001; **p < 0.01; *p ≤ 0.05 versus wild type. B, Neuropathological scoring of HI brain injury in the cerebral cortex (0–4), hippocampus (0–6), striatum (0–6), and thalamus (0–6) is shown. Values are given as mean ± SEM. ***p< 0.001; **p < 0.01 versus wild type.C, The total injury score (0–22) for each animal is shown.