Fig. 5.

Spinal protein synthesis is not required for burst frequency long-term facilitation. The change in burst frequency 15, 30, and 60 min after intermittent hypoxia is shown. Intermittent hypoxia elicits burst frequency long-term facilitation in rats intrathecally injected with artificial CSF (●), emetine (■; 1 μg/kg), or cycloheximide (○; 250 μg/kg). High doses of emetine that were likely not restricted to the spinal cord (▪; 20–250 μg/kg) blocked burst frequency LTF (p > 0.05). *Significantly increased from baseline (p < 0.05).