Table 1.
Clinical data of TLE patients with AHS and autopsy cases used in this study
| Patient | Age | Sex | Onset | Duration | Frequency | Seizure | |
|---|---|---|---|---|---|---|---|
| TLE group 1 (for ISH) | I1 | 17 | M | 14 | 3 | Not known | SPS, CPS |
| I2 | 16 | M | 4.5 | 11.5 | 3–4/month | SPS, CPS | |
| I3 | 32 | F | 2 | 30 | 2–3/month | SPS, CPS | |
| I4 | 53 | M | 38 | 15 | Not known | SPS, CPS | |
| I5 | 31 | M | 2 | 29 | Not known | CPS, sGS | |
| I6 | 39 | F | 1.5 | 37.5 | 2–8/month | SPS, CPS, sGS | |
| I7 | 43 | M | 35 | 8 | 3–4/month | SPS, CPS | |
| I8 | 57 | F | 7 | 50 | Not known | SPS, CPS | |
| I9 | 33 | F | 20 | 13 | 5/month | SPS, CPS, sGS | |
| I10 | 44 | F | 6 | 36 | 3/month | CPS | |
| I11 | 18 | M | 2 | 16 | 2–3/month | SPS, CPS, sGS | |
| I12 | 44 | M | 6 | 38 | 2–3/month | SPS, CPS, sGS | |
| I13 | 40 | M | 30 | 10 | 6–10/year | SPS, CPS, sGS | |
| I14 | 34 | M | 4 | 30 | 2–3/month | SPS, CPS, sGS | |
| I15 | 52 | F | 8 | 44 | 3–4/month | SPS, CPS, sGS | |
| TLE group 2 (for PCR) | P1 | 27 | F | 13 | 14 | 1–3/month | SPS, CPS, sGS |
| P2 | 29 | M | 1.5 | 27 | Not known | SPS, CPS, sGS | |
| P3 | 41 | F | 18 | 23 | 6–7/month | SPS, CPS, sGS | |
| P4 | 32 | M | 8 | 24 | 2/week | SPS, CPS, sGS | |
| P5 | 22 | F | 11 | 11 | 2/week | SPS, CPS | |
| P6 | 38 | M | 8 | 30 | Not known | SPS, CPS | |
| P7 | 37 | F | Not known | Not known | Not known | Not known | |
| Autopsy group 3 | A1 | 24 | M | — | — | — | — |
| A2 | 33 | F | — | — | — | — | |
| A3 | 34 | M | — | — | — | — | |
| A4 | 48 | M | — | — | — | — | |
| A5 | 19 | F | — | — | — | — | |
| A6 | 5 | M | — | — | — | — | |
| A7 | 35 | M | — | — | — | — |
Groups indicate the patients and cases used for ISH and PCR experiments. Age represents the age of the patients at surgery (TLE) or death (autopsy). Onset refers to the age at which a first epileptic seizure was documented. Duration indicates the duration of the epileptic disorder in years. Frequency indicates the frequency of seizure attacks, and seizure indicates the type of seizure (SPS, single partial seizure; sGS, secondary generalized seizure). M, Male; F, female.