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. 2002 Jul 15;22(14):6052–6061. doi: 10.1523/JNEUROSCI.22-14-06052.2002

Fig. 2.

Fig. 2.

Mean frequency of wet-dog shakes (WDS) (top graph), stage 3 seizures (middle graph), and stages 4–6 seizures (bottom graph) per week over the 20 week period after injection of saline (Saline), a single KA (1KA), or triple KA (3KA). One-way ANOVA for repeated measures revealed that saline-treated rats had significantly fewer wet-dog shakes than either the 1KA or 3KA group (F(2,15) = 21.788;p < 0.001). One-way ANOVA also revealed a significant group effect (F(1,11) = 18.542; p < 0.001) and a significant interaction of groups over time (F(3,11) = 10.69;p < 0.001) when the mean frequencies of stages 4–6 seizures were compared. Rats in all groups were observed for SRS for 2–3 hr daily, Monday through Friday, for 20 weeks.