Fig. 5.

Behavioral (A) and electrographic seizure (B) measures of kindling development in WT and trkB^shcmutant mice. Kindling development is presented as behavioral seizure class (A) and electrographic seizure duration as a function of the number of stimulations that evoked electrographic seizures (y-axis). Wild type (+/+;n = 4), heterozygous (+/−; n = 9), and homozygous (−/−; n = 8) mutant mice.ADD# (x-axis) refers to the number of stimulations that evoked an afterdischarge with duration of at least 5 sec. Data are mean ± SEM. Note that neither seizure class nor electrographic seizure duration was significantly different among the three groups (one-way ANOVA).