Table 2.

Differentially regulated genes in the cerebellum of APP_Sw mice

Gene classification	Gene description	FC	ADC	Rank
Amyloid sequestration	Transthyretin	3.21 ± 0.66	21557 ± 2926	16
Apoptosis	Peroxiredoxin 2	1.81 ± 0.88	2730 ± 883	12
	c-fos	−4.57 ± 0.79	−7557 ± 916	−10
Synaptic	Syntaxin 4	2.13 ± 0.36	2536 ± 422	9
Miscellaneous	Ectonucleotide pyrophosphatase/phosphodiesterase 2	2.74 ± 0.68	22165 ± 4904	10
	Eph receptor A7	1.67 ± 0.57	1115 ± 310	12
	Kidney cell line-derived transcript 1	1.64 ± 0.42	840 ± 233	10
	Melanoma antigen, 80 kDa	4.14 ± 0.91	2428 ± 673	10
EST	AA607761	−2.53 ± 0.26	−1370 ± 397	−12

Rank is based on the difference call. Rank values ranging from 9 to 18 indicate increased gene expression (Roman text), and values from −9 to −18 indicate decreased gene expression (italic text). ESTs are listed by their GenBank accession number. FC, Fold change; ADC, average difference change. FC and ADC are expressed as mean ± SEM.