Double-labeling experiments. Retrogradely stained thalamic neurons after implantation of DiASP in the cingulate cortex (open squares) and DiI in the sensorimotor region (filled squares). Composite drawings from three experiments. Left, Wild type; right, ephrin-A5 knock-out mice. A, interaural 2.23, bregma −1.46; B, interaural 1.86, bregma −1.95. Note that, in the absence of ephrin-A5, a group of limbic thalamic cells are miswired and innervate the sensorimotor cortex. VPL, Ventral posterolateral nucleus; VPM, ventral posteromedial nucleus.